FORMULATION& EVALUATION OF CEFUROXIME ORALSUSPENSION FOR PEDIATRICS

Venkata Gopaiah K; N Suresh Kumar J; Gopi Sainath T; Brahmam G; Ashok Chakravarthi M; Harika R; Pujitha V

doi:10.47957/ijciar.v6i1.151

Authors

K.Venkata Gopaiah Associate Professor, Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
J N Suresh Kumar Principal & Professor, Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
T. Gopi Sainath Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
G. Brahmam Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
M. Ashok Chakravarthi Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
R. Harika Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P
V. Pujitha Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Palnadu, A.P

DOI:

https://doi.org/10.47957/ijciar.v6i1.151

Keywords:

Solubility, viscosity, Taste, PH, Sedimentation Volume

Abstract

In the present study we have formulated the cefuroxime oral suspension for pediatrics by masking the taste of the drug which is bitter in taste in the studies we have carried seven trails in the process of masking the taste by change in the concentration of Indion-204 from 2.5gms to 30gms out of all the trails of formulations the final trail S-7 was given the best result in the taste masking of the drug from bitterness of taste. The evaluation parameters carried for all the trails from S-1 to S-7 such, as Solubility, viscosity, Taste, PH, Sedimentation Volume in these entire parameters trail S-7 given the best output result in all the conditions. Finally the bitter taste of the drug was masked by the Drug Resin Complexation method using 30gms of Indion-204 used in the formulation trail S-7.

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