Prevalence of Neonatal Sepsis and its Correlates at Kamoto Mission Hospital in Mambwe District, Eastern Province, Zambia

Hamusonde Sydney, BDS; Kabelenga Elijah, M.Sc.; Muyunda S. Julia, MPH; Mwambazi Mwate, MMed

Authors

Hamusonde Sydney, BDS Michael Chilufya Sata School of Medicine, Copperbelt University, P.O. 7Box 71191, Ndola 10101 Zambia.
Kabelenga Elijah, M.Sc. Michael Chilufya Sata School of Medicine, Copperbelt University, P.O. 7Box 71191, Ndola 10101 Zambia.
Muyunda S. Julia, MPH Ndola Teaching Hospital, Private Agency, Ndola 10101, Zambia
Mwambazi Mwate, MMed Auther Division’s’ Children Hospital, P.O Box, 24022, Ndola 10101, Zambia

Keywords:

Correlates, Kamoto Mission Hospital, Apgar score, Neonatal sepsis

Abstract

Background: Neonatal sepsis (NS) is an infection that occurs in new born babies during the first 28 days of life and causes the majority of neonatal deaths in low-income countries. In the year 2013 and 2014 at Kamoto Mission Hospital, 66 and 104 neonates respectively were treated for septicemia. However, no study has been conducted to determine the current prevalence of neonatal sepsis and its correlates in Mambwe district of Eastern Province. We studied the prevalence of neonatal sepsis and its correlates at Kamoto Mission Hospital in Mambwe district.

Methods: A retrospective non laboratory study involving 156 neonates who were admitted to Kamoto mission Hospital in Mambwe district in 2016 with neonatal sepsis was conducted. SPSS version 21 was used to analyse data. Univariate and bivariate analyses were performed. Variables that were statistically significantly associated with the outcome in bivariate analysis were considered in a logistic multivariate regression analysis. Adjusted odds ratio (AOR) and its 95% confidence intervals are reported.

Result: The prevalence rate of neonatal sepsis was 3.3%. In bivariate analysis, factors that were associated with neonatal sepsis were baby resuscitation, apgar score and birth weight. However, after logistic multivariate analysis, only neonates with an apgar score of less than 7/10 were 3.64 times (AOR= 3.636; p=.002; 95% CI [1.587,8.329]) more likely to have neonatal sepsis compared to those who had a higher apgar score.

Conclusion: Our study has demonstrated the prevalence of neonatal sepsis at Kamoto Mission Hospital of 3.3% and apgar was independently statistically associated neonatal sepsis in Mambwe district. We recommend district health authorities to devise interventions aimed at curbing neonatal sepsis.

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Author Biography

Kabelenga Elijah, M.Sc., Michael Chilufya Sata School of Medicine, Copperbelt University, P.O. 7Box 71191, Ndola 10101 Zambia.

Ndola College of Nursing and Midwifery, Private Agency, Ndola 10101, Zambia.

References

Grant, C. H., Arnott, A., Brook, T., Horne, A., Hurst, W., Kelly, S., Lang, C., Payne, M., Pert, H., Sparrow, S., Dokubo, P.A., Bee, N., Gibbs, R. and Becher, J.C. 2018. Reducing antibiotic exposure in suspected neonatal sepsis. Clinical pediatrics, 57(1): 76-81.

Hayun, M., Alasiry, E., Daud, D., Febriani, D.B. and Madjid, D. 2015. The risk factors of early onset neonatal sepsis. American Journal of Clinical and Experimental Medicine, 3(3): 78-82.

Kamoto Mission Hospital. 2016. Action plan 2015 -2017. Mambwe District.

Leal, Y.A., Álvarez-Nemegyei, J., Velázquez, J.R., Rosado-Quiab, U., Diego-Rodríguez, N., Paz-Baeza, E. and Dávila-Velázquez, J. 2012. Risk factors and prognosis for neonatal sepsis in southeastern Mexico: analysis of a four-year historic cohort follow-up. BMC pregnancy and childbirth, 12(1): 48.

Polin AR. (nd). Diagnosis and Treatment of Neonatal Sepsis: Reconciling the COFN and CDC Guidelines. https://www.se-neonatal.es/Portals/0/Publicaciones/Sepsis%20Neonatal.pdf.

Shah, G.S., Budhathoki, S., Das, B.K. and Mandal, R.N. 2006. Risk factors in early neonatal sepsis. Kathmandu University Medical Journal (KUMJ), 4(2): 187-191.

Sunilbala, K., Periyakaruppan, M., Dipankar De. and Singh, K.I. 2015. Study of Neonatal Outcome with Low Apgar score in Term Neonates. IOSR Journal of Dental and Medical Sciences, 14(11): 59–62.

Waters, D., Jawad, I., Ahmad, A., Lukšić, I., Nair, H., Zgaga, L. Theodoratou, E., Rudan, I., Zaidi, A.K. and Campbell, H. 2011. Aetiology of community-acquired neonatal sepsis in low and middle income countries. Journal of Global Health, 1(2): 154-70.

WHO, 2014. WHO-CC for All India Institute of Medical Sciences, Ansari Nagar, New Delhi -110029.