Immune function of nk cells in cancer and their exploitation in immunotherapeutic

Dharani Panyam

Authors

Panyam Dharani Priyadarshini Institute of Pharmaceutical Education and Research, 5th mile, Pulladigunta, Guntur-522017, Andhra Pradesh, India

Keywords:

Natural Killer Cell, Innate Immunity, Cancer Immunotherapy, Tumor Progression

Abstract

Natural Killer (NK) cells are a type of immune cell that plays a crucial role in defending against tumors and viruses. As part of the innate immune system, NK cells recognize and destroy abnormal cells, preventing tumor development. They are activated upon recognizing abnormal cells and work to eliminate them. Recent research has highlighted the complexity of NK cell responses, including the existence of memory and memory-like NK cell subsets with distinct characteristics and functions. These subsets have been shown to play a key role in immunosurveillance, recognizing and eliminating abnormal cells. NK cells are cytotoxic innate lymphoid cells that produce inflammatory cytokines and chemokines. They are capable of recognizing and destroying transformed or infected cells, making them a key component of the immune response. The role of NK cells in immunity to tumors and viruses has been extensively studied. Research has shown that NK cells are able to recognize and eliminate cancer cells, and that they play a key role in preventing tumor development.

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References

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